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1

A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene

Hecker, Michael, Boxberger, Nina, Illner, Nicole, Fitzner, Brit, Schröder, Ina, Winkelmann, Alexander, Dudesek, Ales, Meister, Stefanie, Koczan, Dirk, Lorenz, Peter, Thiesen, Hans-Jürgen, Zettl, Uwe K

Journal:

Year:

2019

Language:

english

File:

PDF, 4.36 MB

english, 2019

2

Autoimmune pancreatic disease: Preparation of pancreatic juice for proteome analysis

Silke Wandschneider, Volker Fehring, Sophia Jacobs-Emeis, Hans-Jürgen Thiesen, Matthias Löhr

Journal:

ELECTROPHORESIS

Year:

2001

Language:

english

File:

PDF, 3.18 MB

english, 2001

3

Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis

Andrea Sinz, Marcus Bantscheff, Stefan Mikkat, Bruno Ringel, Susanne Drynda, Jörn Kekow, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

ELECTROPHORESIS

Year:

2002

Language:

english

File:

PDF, 451 KB

english, 2002

4

Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins

András Mádi, Stefan Mikkat, Bruno Ringel, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

ELECTROPHORESIS

Year:

2003

Language:

english

File:

PDF, 192 KB

english, 2003

5

Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation

Tobias Böttcher, Eilhard Mix, Dirk Koczan, Peter Bauer, Jens Pahnke, Sabine Peters, Sabine Weinelt, Rupert Knoblich, Ulf Strauss, Elena Cattaneo, Hans-Jürgen Thiesen, Arndt Rolfs

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 470 KB

english, 2003

6

Rheumatoid arthritis, a complex multifactorial disease: On the way toward individualized medicine

Michael O. Glocker, Reinhard Guthke, Jörn Kekow, Hans-Jürgen Thiesen

Journal:

Medicinal Research Reviews

Year:

2006

Language:

english

File:

PDF, 634 KB

english, 2006

7

Mass spectrometric proteome analysis suggests anaerobic shift in metabolism of Dauer larvae of Caenorhabditis elegans

András Mádi, Stefan Mikkat, Cornelia Koy, Bruno Ringel, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2008

Language:

english

File:

PDF, 388 KB

english, 2008

8

Proteome analysis reveals disease-associated marker proteins to differentiate RA patients from other inflammatory joint diseases with the potential to monitor anti-TNFα therapy

Susanne Drynda, Bruno Ringel, Monika Kekow, Cornelia Kühne, Andreas Drynda, Michael O Glocker, Hans-Jürgen Thiesen, Jörn Kekow

Journal:

Pathology - Research and Practice

Year:

2004

Language:

english

File:

PDF, 506 KB

english, 2004

9

A New Cys2/His2 Zinc Finger Gene, rKr2, Is Expressed in Differentiated Rat Oligodendrocytes and Encodes a Protein with a Functional Repressor Domain

Uwe Pott, Hans-Jürgen Thiesen, Raymond J. Colello, Martin E. Schwab

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.33 MB

english, 1995

10

From transcriptome to proteome: Differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies

Peter Lorenz, Peter Ruschpler, Dirk Koczan, Peter Stiehl, Hans-Jürgen Thiesen

Journal:

Year:

2003

Language:

english

File:

PDF, 398 KB

english, 2003

11

Mass spectrometric proteome analysis for profiling temperature-dependent changes of protein expression in wild-type Caenorhabditis elegans

András Mádi, Stefan Mikkat, Bruno Ringel, Markus Ulbrich, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

12

Differential proteome analysis and mass spectrometric characterization of germ line development-related proteins of Caenorhabditis elegans

Marcus Bantscheff, Bruno Ringel, András Madi, Ralf Schnabel, Michael O. Glocker, Hans-Jürgen Thiesen

Journal:

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

13

Age-dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease

Huu Phuc Nguyen, Silke Metzger, Carsten Holzmann, Dirk Koczan, Hans-Jürgen Thiesen, Stephan von Hörsten, Olaf Riess, Michael Bonin

Journal:

PROTEOMICS - Clinical Applications

Year:

2008

Language:

english

File:

PDF, 599 KB

english, 2008

14

Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19

Marie-Françoise Rousseau-Merck, Josette Hillion, Philippe Jonveaux, Philippe Couillin, Paule Seité, Hans-Jürgen Thiesen, Roland Berger

Journal:

Year:

1993

Language:

english

File:

PDF, 1.21 MB

english, 1993

15

Towards a proteome signature for invasive ductal breast carcinoma derived from label-free nanoscale LC-MS protein expression profiling of tumorous and glandular tissue

Claudia Röwer, Johannes P. C. Vissers, Cornelia Koy, Marc Kipping, Michael Hecker, Toralf Reimer, Bernd Gerber, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

Analytical and Bioanalytical Chemistry

Year:

2009

Language:

english

File:

PDF, 317 KB

english, 2009

16

Identification and management of fetuses at risk for, or affected by, congenital heart block associated with autoantibodies to SSA (Ro), SSB (La), or an HsEg5-like autoantigen

Renate Claus, Heiko Hickstein, Thomas Külz, Ute Lenschow, Doris Meiske, Andrea Kotitschke, Hans-Jürgen Thiesen, Peter Lorenz

Journal:

Rheumatology International

Year:

2006

Language:

english

File:

PDF, 361 KB

english, 2006

17

Mass Spectrometric Characterization of Protein Structure Details Refines the Proteome Signature for Invasive Ductal Breast Carcinoma

Claudia Röwer, Cornelia Koy, Michael Hecker, Toralf Reimer, Bernd Gerber, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 541 KB

english, 2011

18

Global epithelial cell transcriptional responses reveal Streptococcus pyogenes Fas regulator activity association with bacterial aggressiveness

Michael Klenk, Dirk Koczan, Reinhard Guthke, Masanobu Nakata, Hans-Jürgen Thiesen, Andreas Podbielski, Bernd Kreikemeyer

Journal:

Cellular Microbiology

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

19

A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas

Lim, Fei Ling, Soulez, Marielle, Koczan, Dirk, Thiesen, Hans-Jürgen, Knight, Jennifer C

Journal:

Year:

1998

Language:

english

File:

PDF, 404 KB

english, 1998

20

Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa by peptide chip and proteome analysis: a pilot study with colorectal carcinoma patient samples

Michael Linnebacher, Peter Lorenz, Cornelia Koy, Annika Jahnke, Nadine Born, Felix Steinbeck, Johannes Wollbold, Tobias Latzkow, Hans-Jürgen Thiesen, Michael O. Glocker

Journal:

Analytical and Bioanalytical Chemistry

Year:

2012

Language:

english

File:

PDF, 398 KB

english, 2012

21

Analysis of aqueous humour proteins of eyes with and without pseudoexfoliation syndrome

Jens Berlau, Peter Lorenz, Ria Beck, Josef Makovitzky, Ursula Schlötzer-Schrehardt, Hans-Jürgen Thiesen, Rudolf Guthoff

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2001

Language:

english

File:

PDF, 43 KB

english, 2001

22

Integration of MicroRNA Databases to Study MicroRNAs Associated with Multiple Sclerosis

Angerstein, Charlotte, Hecker, Michael, Paap, Brigitte Katrin, Koczan, Dirk, Thamilarasan, Madhan, Thiesen, Hans-Jürgen, Zettl, Uwe Klaus

Journal:

Molecular Neurobiology

Year:

2012

Language:

english

File:

PDF, 530 KB

english, 2012

23

Computational analysis of high-density peptide microarray data with application from systemic sclerosis to multiple sclerosis

Michael Hecker, Peter Lorenz, Felix Steinbeck, Li Hong, Gabriela Riemekasten, Yixue Li, Uwe K. Zettl, Hans-Jürgen Thiesen

Journal:

Autoimmunity Reviews

Year:

2012

Language:

english

File:

PDF, 921 KB

english, 2012

24

Inhibitory effects of interferon-γ on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression

Brit Fitzner, Peter Brock, Hana Nechutova, Änne Glass, Thomas Karopka, Dirk Koczan, Hans-Jürgen Thiesen, Gisela Sparmann, Jörg Emmrich, Stefan Liebe, Robert Jaster

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 321 KB

english, 2007

25

Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process

Eilhard Mix, Saleh Ibrahim, Jens Pahnke, Dirk Koczan, Christian Sina, Tobias Böttcher, Hans-Jürgen Thiesen, Arndt Rolfs

Journal:

Journal of Neuroimmunology

Year:

2004

Language:

english

File:

PDF, 522 KB

english, 2004

26

Cloning and sequencing of the bovine STAT5A cDNA reveals significant sequence divergence with ovine

Petra Schröder, Lutz Meyer, Thomas T Wheeler, Hans-Jürgen Thiesen, Hans-Martin Seyfert

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 427 KB

english, 1998

27

Peroxisome proliferator - activated receptor γ overexpression inhibits pro-fibrogenic activities of immortalised rat pancreatic stellate cells

Robert Jaster, Philipp Lichte, Brit Fitzner, Peter Brock, Änne Glass, Thomas Karopka, Lothar Gierl, Dirk Koczan, Hans-Jürgen Thiesen, Gisela Sparmann, Jörg Emmrich, Stefan Liebe

Journal:

Journal of Cellular and Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 451 KB

english, 2005

28

Robust computational reconstitution – a new method for the comparative analysis of gene expression in tissues and isolated cell fractions

Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-Jürgen Thiesen, Stefan Wölfl, Raimund W Kinne

Journal:

BMC Bioinformatics

Year:

2006

Language:

english

File:

PDF, 422 KB

english, 2006

29

Expression profiling of a high-fertility mouse line by microarray analysis and qPCR

Jens Vanselow, Gerd Nürnberg, Dirk Koczan, Martina Langhammer, Hans-Jürgen Thiesen, Norbert Reinsch

Journal:

Year:

2008

Language:

english

File:

PDF, 951 KB

english, 2008

30

Clustered Organization of Krüppel Zinc-Finger Genes at Xp11.23, Flanking a Translocation Breakpoint at OATL1: A Physical Map with Locus Assignments for ZNF21, ZNF41, ZNF81, and ELK1

Jennifer C. Knight, Giovanna Grimaldi, Hans-Jürgen Thiesen, N.Torben Bech-Hansen, Christopher D.M. Fletcher, Michael P. Coleman

Journal:

Year:

1994

File:

PDF, 613 KB

1994

31

Gene-Expression Profile of Collagen-induced Arthritis

Saleh Mohamed Ibrahim, Dirk Koczan, Hans-Jürgen Thiesen

Journal:

Journal of Autoimmunity

Year:

2002

Language:

english

File:

PDF, 443 KB

english, 2002

32

Determination of DNA binding specificities of mutated zinc finger domains

Hans-Jürgen Thiesen, Christian Bach

Journal:

Year:

1991

Language:

english

File:

PDF, 779 KB

english, 1991

33

Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells

Jens Pahnke, Eilhard Mix, Rupert Knoblich, Jana Müller, Marlies Zschiesche, Beke Schubert, Dirk Koczan, Peter Bauer, Tobias Böttcher, Hans-Jürgen Thiesen, Ludmil Lazarov, Andreas Wree, Arndt Rolfs

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 498 KB

english, 2004

34

Anoxia-Induced Up-Regulation of Interleukin-8 in Human Malignant Melanoma: A Potential Mechanism for High Tumor Aggressiveness

Manfred Kunz, Anke Hartmann, Egbert Flory, Atiye Toksoy, Dirk Koczan, Hans-Jürgen Thiesen, Nafoumi Mukaida, Manfred Neumann, Ulf Rüdiger Rapp, Eva-Bettina Bröcker, Reinhard Gillitzer

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 2.07 MB

english, 1999

35

Transition metals modulate DNA-protein interactions of SP1 zinc finger domains with its cognate target site

Hans-Jurgen Thiesen, Christian Bach

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 935 KB

english, 1991

36

Amino acid substitutions in the SP1 zinc finger domain alter the DNA binding affinity to cognate SP1 target site

Hans-Jurgen Thiesen, Bjorn Schroder

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 765 KB

english, 1991

37

Cell type specificity of signaling: view from membrane receptors distribution and their downstream transduction networks

Ying He, Zhonghao Yu, Dongya Ge, Rui Wang-Sattler, Hans-Jürgen Thiesen, Lu Xie, Yixue Li

Journal:

Year:

2012

Language:

english

File:

PDF, 887 KB

english, 2012

38

DNA Recognition of C2H2 Zinc-Finger Proteins : Evidence for a Zinc-Finger-specific DNA Recognition Code

HANS-JÜRGEN THIESEN, CHRISTIAN BACH

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 237 KB

english, 1993

39

Krab Domains Analyzed in Human Cys/His-Type Zinc-Finger Proteins KOX 1, KOX 8, and KOX 19

HANS-JÜRGEN THIESEN, WOLFRAM MEYER

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 143 KB

english, 1993

40

Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis

Xinhua Yu, Kristin Bauer, Dirk Koczan, Hans-Jürgen Thiesen…

Journal:

Arthritis Research & Therapy

Year:

2007

Language:

english

File:

PDF, 533 KB

english, 2007

41

MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients

Hecker, Michael, Thamilarasan, Madhan, Koczan, Dirk, Schröder, Ina, Flechtner, Kristin, Freiesleben, Sherry, Füllen, Georg, Thiesen, Hans-Jürgen, Zettl, Uwe

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 685 KB

english, 2013

42

Target Detection Assay (TDA): a versatile procedure to determine DNA blinding sites as demonstrated on SP1 protein

Thiesen, Hans-jürgen, Bach, Christian

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 4.41 MB

english, 1990

43

A novel strategy for the rapid preparation and isolation of intact immune complexes from peptide mixtures

Al-Majdoub, Mahmoud, Opuni, Kwabena F. M., Yefremova, Yelena, Koy, Cornelia, Lorenz, Peter, El-Kased, Reham F., Thiesen, Hans-Jürgen, Glocker, Michael O.

Journal:

Journal of Molecular Recognition

Year:

2014

Language:

english

File:

PDF, 1.13 MB

english, 2014

44

miRNA expression profiles determined in maternal sera of patients with HELLP syndrome

Stubert, Johannes, Koczan, Dirk, Richter, Dagmar-Ulrike, Dieterich, Max, Ziems, Björn, Thiesen, Hans-Jürgen, Gerber, Bernd, Reimer, Toralf

Journal:

Hypertension in Pregnancy

Year:

2014

Language:

english

File:

PDF, 604 KB

english, 2014

45

Developmentally Regulated Mouse Gene NK10 Encodes a Zinc Finger Repressor Protein with Differential DNA-Binding Domains

LANGE, RITA, CHRISTOPH, ANNETTE, THIESEN, HANS-JÜRGEN, VOPPER, GABY, JOHNSON, KENNETH R., LEMAIRE, LYDIA, PLOMANN, MARKUS, CREMER, HAROLD, BARTHELS, DAGMAR, HEINLEIN, UWE A.O.

Journal:

DNA and Cell Biology

Year:

1995

Language:

english

File:

PDF, 12.64 MB

english, 1995

46

From Transcription Profile to Expression: The Signaling Repertoire of the SK-N-MC Neuroepithelioma Cell-Line

Bader, Jürgen E., Deckert, Cornelia M., Koglin, Norman, Pluder, Franka, Mörl, Karin, Koczan, Dirk, Thiesen, Hans-Jürgen, Beck-Sickinger, Annette G.

Journal:

Journal of Receptor and Signal Transduction Research

Year:

2004

Language:

english

File:

PDF, 408 KB

english, 2004

47

A Banll RFLP in the ZNF34 zinc finger gene on chromosome 8

Pillo, Biagio La, Lüdecke, Hermann-Josef, Thiesen, Hans-Jürgen, Horsthemke, Bernhard

Journal:

Human Molecular Genetics

Year:

1993

Language:

english

File:

PDF, 1.58 MB

english, 1993

48

Transcriptional Repression Mediated by the KRAB Domain of the Human C2H2 Zinc Finger Protein Kox1/ZNF10 Does Not Require Histone Deacetylation

Lorenz, Peter, Koczan, Dirk, Thiesen, Hans-Jürgen

Journal:

Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 292 KB

english, 2001

49

Silencing of RNA Polymerases II and III-Dependent Transcription by the KRAB Protein Domain of KOX1, a Krüppel-Type Zinc Finger Factor

Moosmann, Peter, Georgiev, Oleg, Thiesen, Hans-Jürgen, Hagmann, Michael, Schaffner, Walter

Journal:

Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 2.16 MB

english, 1997

50

Proteome Analysis of Diseased Joints from Mice Suffering from Collagen-Induced Arthritis

Lorenz, Peter, Bantscheff, Marcus, Ibrahim, Saleh M., Thiesen, Hans-Jürgen, Glocker, Michael O.

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2003

Language:

english

File:

PDF, 694 KB

english, 2003